Original article

Blood Transfusion - 2 2021 (March-April)

SARS-Cov-2/COVID-19 pandemic: first wave, impact, response and lessons learnt in a fully integrated regional blood and tissue bank. A narrative report

Authors

Key words: COVID-19, pandemic, blood and tissue bank
Publication Date: 2021-01-15

Abstract

Background - The COVID-19 pandemic is placing blood and tissue establishments under unprecedented stress, putting its capacity to provide the adequate care needed at risk. Here we reflect on how our integrated organisational model has faced the first impact of the pandemic and describe what challenges, opportunities and lessons have emerged.
Materials and methods - The organisational model of the Catalan Blood and Tissue Bank (Banc de Sang i Teixits, BST) is described. The new scenario was managed by following international recommendations and considering the pandemic in a context of volatility, uncertainty, complexity, and ambiguity (VUCA), allowing rapid measures to be taken. These aimed to: ensure donor safety, promote proper responses to patients’ needs, ensure the health and well-being of personnel, and prepare for future scenarios.
Results - The BST has adapted its activities to the changes in demand. No shortage of any product or service occurred. Donor acceptance, safety and wellbeing were maintained except for tissue donation, which almost completely stopped. To support the health system, several activities have been promoted: large-scale convalescent plasma (CP) production, clinical trials with CP and mesenchymal stromal cells, massive COVID-19 diagnoses, and participation in co-operative research and publications. Haemovigilance is running smoothly and no adverse effects have been detected among donors or patients.
Discussion - Several elements have proven to be critical when addressing the pandemic scenario: a) the early creation of a crisis committee in combination with technical recommendations and the recognition of a VUCA scenario; b) identification of the strategies described; c) the integrated donor-to-patient organisational model; d) active Research and Development (R&D); and e) the flexibility of the staff. It is essential to underline the importance of the need for centralised management, effective contingency strategies, and early collaboration with peers.

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Authors

Joan Garcia-Lopez - Banc de Sang i Teixits (BST), Barcelona, Spain; Chair of Transfusion Medicine and Cellular and Tissue Therapies, Universitat Autònoma de Barcelona (UAB), Barcelona, Spain

Joaquin Delgadillo - Banc de Sang i Teixits (BST), Barcelona, Spain

Anna Vilarrodona - Banc de Sang i Teixits (BST), Barcelona, Spain

Sergi Querol - Banc de Sang i Teixits (BST), Barcelona, Spain

Joan Ovejo - Banc de Sang i Teixits (BST), Barcelona, Spain

Ruth Coll - Banc de Sang i Teixits (BST), Barcelona, Spain

Anna Millan - Banc de Sang i Teixits (BST), Barcelona, Spain

Alejandro Madrigal - Banc de Sang i Teixits (BST), Barcelona, Spain; UCL Cancer institute, Royal Free Hospital, London, United Kingdom

Gloria Soria - Banc de Sang i Teixits (BST), Barcelona, Spain

Francisco Vidal - Banc de Sang i Teixits (BST), Barcelona, Spain

Joaquim Vives - Banc de Sang i Teixits (BST), Barcelona, Spain; Chair of Transfusion Medicine and Cellular and Tissue Therapies, Universitat Autònoma de Barcelona (UAB), Barcelona, Spain; Musculoskeletal Tissue Engineering Group, Vall d'Hebron Research Institute (VHIR), Barcelona, Spain

María J. Herrero - Banc de Sang i Teixits (BST), Barcelona, Spain

Isabel Lopez - Banc de Sang i Teixits (BST), Barcelona, Spain

Silvia Sauleda - Banc de Sang i Teixits (BST), Barcelona, Spain

Enric Contreras - Banc de Sang i Teixits (BST), Barcelona, Spain; Chair of Transfusion Medicine and Cellular and Tissue Therapies, Universitat Autònoma de Barcelona (UAB), Barcelona, Spain

Joan Ramon Grifols - Banc de Sang i Teixits (BST), Barcelona, Spain

Rosa Guasch - Banc de Sang i Teixits (BST), Barcelona, Spain

Elisabet Tahull - Banc de Sang i Teixits (BST), Barcelona, Spain

Lluís Puig - Banc de Sang i Teixits (BST), Barcelona, Spain

Aurora Masip - Banc de Sang i Teixits (BST), Barcelona, Spain

Enric Argelagués - Banc de Sang i Teixits (BST), Barcelona, Spain

Eduardo Muñiz-Diaz - Banc de Sang i Teixits (BST), Barcelona, Spain; Chair of Transfusion Medicine and Cellular and Tissue Therapies, Universitat Autònoma de Barcelona (UAB), Barcelona, Spain

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