Evans syndrome and infections: a dangerous cocktail to manage with caution

Abstract

Preview
Evans syndrome (ES) is a rare condition characterised by the association of multiple autoimmune cytopenias, usually autoimmune haemolytic anaemia (AIHA) and immune thrombocytopenia (ITP), and, although rarely, autoimmune neutropenia. Up to 50% of ES cases may be secondary to a variety of conditions including infections, primary immunodeficiencies, particularly in children, systemic autoimmune diseases (such as systemic lupus erythematosus and rheumatoid arthritis), lymphoproliferative syndromes, and transplantation. [ … ]