Abstract
Introduction
Pathogen reduction technologies have been developed to reduce the risk of transmission of infectious agents through blood transfusion1. The Mirasol® Pathogen Reduction Technology (PRT) System from Terumo BCT (Lakewood, CO, USA) uses ultraviolet light and riboflavin (vitamin B2) to reduce the load of active pathogens and to inactivate residual white blood cells in blood components used for transfusion2. A CE mark was granted for the Mirasol® PRT System in 2007 for use with apheresis and buffy coat platelets stored in 100% plasma, and subsequently CE marks were granted in 2008 and 2009 for the system's use in the treatment of plasma and platelets stored in platelet additive solution, respectively. [...]
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