Management of iron overload in myelodysplastic syndromes: combined deferasirox and deferoxamine in a patient with liver disease

Claudio Cerchione; Giuseppe Cerciello; Simona Avilia; Roberta Della Pepa; Novella Pugliese; Marco Picardi; Lucio Catalano; Fabrizio Pane

doi:10.2450/2016.0137-16

Case report

Blood Transfusion - 1 2018 (January - February)

Management of iron overload in myelodysplastic syndromes: combined deferasirox and deferoxamine in a patient with liver disease

Claudio Cerchione , Giuseppe Cerciello , Simona Avilia , Roberta Della Pepa , Novella Pugliese , Marco Picardi , Lucio Catalano , Fabrizio Pane

DOI: 10.2450/2016.0137-16

Publication Date: 2016-10-24

Abstract

Introduction
Myelodysplastic syndromes (MDS) are a heterogeneous group of clonal disorders of haematopoietic stem cells, characterised by ineffective haematopoiesis leading to peripheral cytopenias and hypercellular bone marrow, with increased propensity to progression to acute myeloid leukaemia. Anaemia is the most common symptom: it may precipitate symptoms in patients with cardiac disorders, thus affecting the patients' outcome. [...]

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Claudio Cerchione - Haematology Division, "Federico II" University Hospital, Naples, Italy

Giuseppe Cerciello - Haematology Division, "Federico II" University Hospital, Naples, Italy

Simona Avilia - Haematology Division, "Federico II" University Hospital, Naples, Italy

Roberta Della Pepa - Haematology Division, "Federico II" University Hospital, Naples, Italy

Novella Pugliese - Haematology Division, "Federico II" University Hospital, Naples, Italy

Marco Picardi - Haematology Division, "Federico II" University Hospital, Naples, Italy

Lucio Catalano - Haematology Division, "Federico II" University Hospital, Naples, Italy

Fabrizio Pane - Haematology Division, "Federico II" University Hospital, Naples, Italy

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PLASTIC RECONSTRUCTIVE AND REGENERATIVE SURGERY

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