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PLASTIC RECONSTRUCTIVE AND REGENERATIVE SURGERY

Abstract

The presence of ABO subgroup alleles and abnormal O alleles is often associated with inconsistent serologic findings in ABO blood group typing. ABO phenotypes were identified by standard serological agglutination tests and allele direct sequencing and haplotype sequencing analyses of the ABO gene were carried out. The serologic results showed the female case was preliminarily assigned as A2 subtype. The sequencing results showed the patient was heterozygous for a novel O allele (c.801G>T) and A205, which caused a p.Gly267Gly synonymous variant.

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Authors

Chonghe Xu - School of Basic Medical Sciences, Capital Medical University, Beijing, China

Zhongqi Zhu - Department of Clinical Laboratory, Affiliated Chaohu Hospital of Anhui Medical University, Chaohu, China

Mei Zhu - Department of Clinical Laboratory, Affiliated Chaohu Hospital of Anhui Medical University, Chaohu, China

Wei Xu - Department of Blood Transfusion, First Affiliated Hospital of Anhui Medical University, Hefei, China

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